I haven't lived in the area for over 10 years, which was before I started smoking cigars, so no good info on smoke shops. Try the Cajun cuisine. The blue crabs should be in prime season right now. Paul Prudome's sister had a nice restaurant a little north of Lafayette on I45(?). There should some decent places to eat in Breaux Bridge (east of Laf), it is the crawfish capital, but crawfish are out of season right now.
Enjoy,
Ken